产品详情
简单介绍:
Human MMP19 (Matrix Metalloproteinase 19) Sandwich ELISA Kit Ready-To-Use (STJE0017049)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.109ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This MMP19 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | MMP19 |
Gene ID: | 4327 |
Uniprot ID: | MMP19_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients. |
Post Translational Modifications | Activated by autolytic cleavage after Lys-97. Tyrosine phosphorylated by PKDCC/VLK. |
Function | Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin. |
Protein Name | Matrix Metalloproteinase-19 Mmp-19 Matrix Metalloproteinase Rasi Matrix Metalloproteinase-18 Mmp-18 |
Database Links | Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
Alternative ELISA Names | Matrix Metalloproteinase-19 ELISA kit Mmp-19 ELISA kit Matrix Metalloproteinase Rasi ELISA kit Matrix Metalloproteinase-18 ELISA kit Mmp-18 ELISA kit MMP19 ELISA kit MMP18 ELISA kit RASI ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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