产品详情
简单介绍：
Anti-CD273/PDCD1LG2 antibody [24F.10C12] {PE} (STJA0001964)
详情介绍：
| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-Programmed cell death 1 ligand 2 is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 24F.10C12 |
| Conjugation: | PE |
| Isotype: | IgG2ak |
| Formulation: | PBS with 0.05% Proclin300, 1% BSA |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | PDCD1LG2 |
| Gene ID: | 80380 |
| Uniprot ID: | PD1L2_HUMAN |
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2 Pd-1 Ligand 2 Pd-L2 Pdcd1 Ligand 2 Programmed Death Ligand 2 Butyrophilin B7-Dc B7-Dc Cd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: Secreted Isoform 2: Endomembrane System Single-Pass Type I Membrane Protein Isoform 1: Cell Membrane |
| Alternative Antibody Names | Anti-Programmed Cell Death 1 Ligand 2 antibody Anti-Pd-1 Ligand 2 antibody Anti-Pd-L2 antibody Anti-Pdcd1 Ligand 2 antibody Anti-Programmed Death Ligand 2 antibody Anti-Butyrophilin B7-Dc antibody Anti-B7-Dc antibody Anti-Cd Antigen Cd273 antibody Anti-PDCD1LG2 antibody Anti-B7DC antibody Anti-CD273 antibody Anti-PDCD1L2 antibody Anti-PDL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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