产品详情
简单介绍:
Human PAOX (Polyamine Oxidase) Sandwich ELISA Kit (STJE0011269)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 31.5pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description: | This PAOX Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | PAOX |
Gene ID: | 196743 |
Uniprot ID: | PAOX_HUMAN |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. |
Post Translational Modifications | |
Function | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
Protein Name | Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase Polyamine Oxidase |
Database Links | Reactome: R-HSA-141334 Reactome: R-HSA-351200 Reactome: R-HSA-9033241 |
Cellular Localisation | Peroxisome Cytoplasm |
Alternative ELISA Names | Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase ELISA kit Polyamine Oxidase ELISA kit PAOX ELISA kit PAO ELISA kit UNQ1923 ELISA kit PRO4398 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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