产品详情
简单介绍:
Human PLOD3 (Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3) Sandwich ELISA Kit (STJE0011560)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.106ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This PLOD3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | PLOD3 |
Gene ID: | 8985 |
Uniprot ID: | PLOD3_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Ubiquitous. Detected in heart, placenta and pancreas and at lower levels in lung, liver and skeletal muscle. |
Post Translational Modifications | |
Function | Multifunctional enzyme that catalyzes a series of essential post-translational modifications on Lys residues in procollagen. Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine. Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues. Essential for normal biosynthesis and secretion of type IV collagens (Probable). Essential for normal formation of basement membranes. |
Protein Name | Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3 Includes - Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 3 Lysyl Hydroxylase 3 Lh3 - Procollagen Glycosyltransferase Galactosylhydroxylysine-Glucosyltransferase Procollagen Galactosyltransferase Procollagen Glucosyltransferase |
Database Links | Reactome: R-HSA-1650814 |
Cellular Localisation | Rough Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Peripheral Membrane Protein Lumenal Side Secreted Extracellular Space The Majority Of The Secreted Protein Is Associated With The Extracellular Matrix |
Alternative ELISA Names | Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3 Includes - Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 3 ELISA kit Lysyl Hydroxylase 3 ELISA kit Lh3 - Procollagen Glycosyltransferase ELISA kit Galactosylhydroxylysine-Glucosyltransferase ELISA kit Procollagen Galactosyltransferase ELISA kit Procollagen Glucosyltransferase ELISA kit PLOD3 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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