产品详情
简单介绍:
Anti-CAMK1D antibody (1-180) (STJ115396)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CAMK1D (1-180) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CAMK1D |
Gene ID: | 57118 |
Uniprot ID: | KCC1D_HUMAN |
Immunogen Region: | 1-180 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CAMK1D (NP_705718.1). |
Immunogen Sequence: | MARENGESSSSWKKQAEDIK KIFEFKETLGTGAFSEVVLA EEKATGKLFAVKCIPKKALK GKESSIENEIAVLRKIKHEN IVALEDIYESPNHLYLVMQL VSGGELFDRIVEKGFYTEKD ASTLIRQVLDAVYYLHRMGI VHRDLKPENLLYYSQDEESK IMISDFGLSKMEGKGDVMST |
Tissue Specificity | Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. |
Function | Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta. |
Protein Name | Calcium/Calmodulin-Dependent Protein Kinase Type 1d Cam Kinase I Delta Cam Kinase Id Cam-Ki Delta Camki Delta Camkid Camki-Like Protein Kinase Cklik |
Cellular Localisation | Cytoplasm Nucleus Predominantly Cytoplasmic Nuclear Localization Increases Upon Activation By Kcl Treatment In Hippocampal Neurons |
Alternative Antibody Names | Anti-Calcium/Calmodulin-Dependent Protein Kinase Type 1d antibody Anti-Cam Kinase I Delta antibody Anti-Cam Kinase Id antibody Anti-Cam-Ki Delta antibody Anti-Camki Delta antibody Anti-Camkid antibody Anti-Camki-Like Protein Kinase antibody Anti-Cklik antibody Anti-CAMK1D antibody Anti-CAMKID antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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