产品详情
  • 产品名称:Anti-CAMK1D antibody (1-180) (STJ115396)

  • 产品型号:STJ115396
  • 产品厂商:ST john's laboratory
  • 产品文档:
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简单介绍:
Anti-CAMK1D antibody (1-180) (STJ115396)
详情介绍:
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CAMK1D (1-180) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAMK1D
Gene ID: 57118
Uniprot ID: KCC1D_HUMAN
Immunogen Region: 1-180
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CAMK1D (NP_705718.1).
Immunogen Sequence: MARENGESSSSWKKQAEDIK KIFEFKETLGTGAFSEVVLA EEKATGKLFAVKCIPKKALK GKESSIENEIAVLRKIKHEN IVALEDIYESPNHLYLVMQL VSGGELFDRIVEKGFYTEKD ASTLIRQVLDAVYYLHRMGI VHRDLKPENLLYYSQDEESK IMISDFGLSKMEGKGDVMST
Tissue Specificity Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
Function Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Protein Name Calcium/Calmodulin-Dependent Protein Kinase Type 1d
Cam Kinase I Delta
Cam Kinase Id
Cam-Ki Delta
Camki Delta
Camkid
Camki-Like Protein Kinase
Cklik
Cellular Localisation Cytoplasm
Nucleus
Predominantly Cytoplasmic
Nuclear Localization Increases Upon Activation By Kcl Treatment In Hippocampal Neurons
Alternative Antibody Names Anti-Calcium/Calmodulin-Dependent Protein Kinase Type 1d antibody
Anti-Cam Kinase I Delta antibody
Anti-Cam Kinase Id antibody
Anti-Cam-Ki Delta antibody
Anti-Camki Delta antibody
Anti-Camkid antibody
Anti-Camki-Like Protein Kinase antibody
Anti-Cklik antibody
Anti-CAMK1D antibody
Anti-CAMKID antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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