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  • 产品名称：Anti-CAPG antibody (1-188) [S5MR] (STJ11103565)

  • 产品型号：STJ11103565
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CAPG antibody (1-188) [S5MR] (STJ11103565)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-CAPG (1-188) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S5MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAPG
Gene ID: 822
Uniprot ID: CAPG_HUMAN
Immunogen Region: 1-188
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human CAPG (P40121).
Immunogen Sequence: MYTAIPQSGSPFPGSVQDPG LHVWRVEKLKPVPVAQENQG VFFSGDSYLVLHNGPEEVSH LHLWIGQQSSRDEQGACAVL AVHLNTLLGERPVQHREVQG NESDLFMSYFPRGLKYQEGG VESAFHKTSTGAPAAIKKLY QVKGKKNIRATERALNWDSF NTGDCFILDLGQNIFAWCGG KSNILERN
Tissue Specificity Macrophages and macrophage-like cells.
Post Translational Modifications The N-terminus is blocked.
Function Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Protein Name Macrophage-Capping Protein
Actin Regulatory Protein Cap-G
Cellular Localisation Nucleus
Cytoplasm
Melanosome
Cell Projection
Lamellipodium
Ruffle
In Macrophages
May Be Predominantly Cytoplasmic
Nuclear Localization Was Observed In Fibroblasts
Present At The Membrane-Cytoplasm Interface
In Activated Macrophages
Concentrated In The Ruffles Of The Leading Lamellipodia
Alternative Antibody Names Anti-Macrophage-Capping Protein antibody
Anti-Actin Regulatory Protein Cap-G antibody
Anti-CAPG antibody
Anti-AFCP antibody
Anti-MCP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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