产品详情
简单介绍:
Anti-CGN antibody (904-1203) (STJ117684)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CGN (904-1203) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:200-1:2000 IHC-P 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CGN |
Gene ID: | 57530 |
Uniprot ID: | CING_HUMAN |
Immunogen Region: | 904-1203 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 904-1203 of human CGN (NP_065821.1). |
Immunogen Sequence: | TSGGLSRLQDEIQRLRQALQ ASQAERDTARLDKELLAQRL QGLEQEAENKKRSQDDRARQ LKGLEEKVSRLETELDEEKN TVELLTDRVNRGRDQVDQLR TELMQERSARQDLECDKISL ERQNKDLKTRLASSEGFQKP SASLSQLESQNQLLQERLQA EEREKTVLQSTNRKLERKVK ELSIQIEDERQHVNDQKDQL SLRVKALKRQVDEAEEEIER LDGLRKKAQREVEEQHEVN |
Tissue Specificity | Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart. |
Function | Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. |
Protein Name | Cingulin |
Database Links | Reactome: R-HSA-2173791 |
Cellular Localisation | Cell Junction Tight Junction Localizes To The Apical Junction Complex Composed Of Tight And Adherens Junctions Colocalizes With Spef1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
Alternative Antibody Names | Anti-Cingulin antibody Anti-CGN antibody Anti-KIAA1319 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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