产品详情
简单介绍:
Human SF3B3 (Splicing Factor 3B Subunit 3) Sandwich ELISA Kit (STJE0012116)
详情介绍:
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.065ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This SF3B3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | SF3B3 |
| Gene ID: | 23450 |
| Uniprot ID: | SF3B3_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | Splicing Factor 3b Subunit 3 Pre-Mrna-Splicing Factor Sf3b 130 Kda Subunit Sf3b130 Staf130 Spliceosome-Associated Protein 130 Sap 130 |
| Database Links | Reactome: R-HSA-72163 Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Splicing Factor 3b Subunit 3 ELISA kit Pre-Mrna-Splicing Factor Sf3b 130 Kda Subunit ELISA kit Sf3b130 ELISA kit Staf130 ELISA kit Spliceosome-Associated Protein 130 ELISA kit Sap 130 ELISA kit SF3B3 ELISA kit KIAA0017 ELISA kit SAP130 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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