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  • 产品名称：Human SFN (Stratifin) Sandwich ELISA Kit (STJE0012118)

  • 产品型号：STJE0012118
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human SFN (Stratifin) Sandwich ELISA Kit (STJE0012118)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.134ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This SFN Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SFN
Gene ID: 2810
Uniprot ID: 1433S_HUMAN
Sample Type: serum, plasma, cerebrospinal fluid or other biological fluids.
Tissue Specificity Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
Post Translational Modifications Ubiquitinated. Ubiquitination by RFFL induces proteasomal degradation and indirectly regulates p53/TP53 activation.
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. p53-regulated inhibitor of G2/M progression.
Protein Name 14-3-3 Protein Sigma
Epithelial Cell Marker Protein 1
Stratifin
Database Links Reactome: R-HSA-111447
Reactome: R-HSA-1445148
Reactome: R-HSA-5625740
Reactome: R-HSA-5628897
Reactome: R-HSA-6804114
Reactome: R-HSA-75035
Reactome: R-HSA-9614399
Reactome: R-HSA-9735871
Reactome: R-HSA-9755779
Cellular Localisation Cytoplasm
Nucleus
Secreted
May Be Secreted By A Non-Classical Secretory Pathway
Alternative ELISA Names 14-3-3 Protein Sigma ELISA kit
Epithelial Cell Marker Protein 1 ELISA kit
Stratifin ELISA kit
SFN ELISA kit
HME1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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