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  • 产品名称：Human SIAL2 (Sialidase 2, Cytosolic) Sandwich ELISA Kit (STJE0012159)

  • 产品型号：STJE0012159
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human SIAL2 (Sialidase 2, Cytosolic) Sandwich ELISA Kit (STJE0012159)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.082ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This SIAL2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: NEU2
Gene ID: 4759
Uniprot ID: NEUR2_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1.
Post Translational Modifications
Function Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Recognizes sialyl linkage positions of the glycan moiety as well as the supramolecular organization of the sialoglycoconjugate. Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles. Hydrolyzes monomeric GM1 ganglioside, but has no activity toward the miscellar form. Has lower sialidase activity for glycoproteins such as fetuin and TF/transferrin that carry a mixture of alpha-(2->3) and alpha-(2->6)-sialyl linkages. Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward alpha-(2->6)-sialyllactose isomer. Has no activity toward colominic acid, a homomer of alpha-(2->8)-linked Neu5Ac residues.
Protein Name Sialidase-2
Cytosolic Sialidase
N-Acetyl-Alpha-Neuraminidase 2
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-4085001
Cellular Localisation Cytoplasm
Cytosol
Alternative ELISA Names Sialidase-2 ELISA kit
Cytosolic Sialidase ELISA kit
N-Acetyl-Alpha-Neuraminidase 2 ELISA kit
NEU2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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