产品详情
简单介绍:
Anti-CHMP7 antibody (204-453) (STJ116546)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CHMP7 (204-453) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CHMP7 |
Gene ID: | 91782 |
Uniprot ID: | CHMP7_HUMAN |
Immunogen Region: | 204-453 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-453 of human CHMP7 (NP_689485.1). |
Immunogen Sequence: | LQKEKRVTVLEQNGEKIVKF ARGPRAKVSPVNDVDVGVYQ LMQSEQLLSRKVESLSQEAE RCKEEARRACRAGKKQLALR SLKAKQRTEKRIEALHAKLD TVQGILDRIYASQTDQMVFN AYQAGVGALKLSMKDVTVEK AESLVDQIQELCDTQDEVSQ TLAGGVTNGLDFDSEELEKE LDILLQDTTKEPLDLPDNPR NRHFTNSVPNPRISDAELEA ELEKLSLSEGGLVPSSKSP |
Function | ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase. Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase. Recruited to the reforming NE during anaphase by LEMD2. Plays a role in the endosomal sorting pathway. |
Protein Name | Charged Multivesicular Body Protein 7 Chromatin-Modifying Protein 7 |
Database Links | Reactome: R-HSA-162588 Reactome: R-HSA-1632852 Reactome: R-HSA-5620971 Reactome: R-HSA-917729 Reactome: R-HSA-9610379 Reactome: R-HSA-9615710 Reactome: R-HSA-9668328 Reactome: R-HSA-9679504 Reactome: R-HSA-9694676 |
Cellular Localisation | Cytoplasm Nucleus Envelope Diffused Localization With Some Punctate Distribution Especially In The Perinuclear Area Localizes To The Reforming Nuclear Envelope On Chromatin Disks During Late Anaphase |
Alternative Antibody Names | Anti-Charged Multivesicular Body Protein 7 antibody Anti-Chromatin-Modifying Protein 7 antibody Anti-CHMP7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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