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  • 产品名称：Anti-CHRM3 antibody (390-590) (STJ29860)

  • 产品型号：STJ29860
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CHRM3 antibody (390-590) (STJ29860)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CHRM3 (390-590) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHRM3
Gene ID: 1131
Uniprot ID: ACM3_HUMAN
Immunogen Region: 390-590
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 390-590 of human CHRM3 (NP_000731.1).
Immunogen Sequence: QVPEEELGMVDLERKADKLQ AQKSVDDGGSFPKSFSKLPI QLESAVDTAKTSDVNSSVGK STATLPLSFKEATLAKRFAL KTRSQI
Function The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Protein Name Muscarinic Acetylcholine Receptor M3
Database Links Reactome: R-HSA-390648
Reactome: R-HSA-399997
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Postsynaptic Cell Membrane
Basolateral Cell Membrane
Endoplasmic Reticulum Membrane
Colocalizes With Tmem147 In The Endoplasmic Reticulum (Er) Membrane
Tmem147 Impairs Its Trafficking To The Cell Membrane Leading To Its Retention In The Er Membrane
Alternative Antibody Names Anti-Muscarinic Acetylcholine Receptor M3 antibody
Anti-CHRM3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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