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  • 产品名称：Anti-CAV3 antibody (N-Term) (STJ71896)

  • 产品型号：STJ71896-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CAV3 antibody (N-Term) (STJ71896)
详情介绍：
Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat/Dog/Cow/Pig
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CAV3 (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-Recommended concentration, 3-5µg/ml
ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CAV3
Gene ID: 859
Uniprot ID: CAV3_HUMAN
Immunogen Region: N-Term
Accession Number: NP_203123.1
Specificity: Reported variants represent identical protein (NP_001225.1; NP_203123.1).
Immunogen Sequence: EHTDLEAQIVKDIH
Post Translational Modifications Sumoylation with SUMO3 by PIAS4 may reduce agonist-induced internalization and desensitization of adrenergic receptor ABRD2.
Function May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae.
Protein Name Caveolin-3
M-Caveolin
Database Links Reactome: R-HSA-445355
Cellular Localisation Golgi Apparatus Membrane
Peripheral Membrane Protein
Cell Membrane
Membrane
Caveola
Sarcolemma
Potential Hairpin-Like Structure In The Membrane
Membrane Protein Of Caveolae
Alternative Antibody Names Anti-Caveolin-3 antibody
Anti-M-Caveolin antibody
Anti-CAV3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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