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  • 产品名称：Anti-CAVIN2 antibody (325-425) (STJ11105248)

  • 产品型号：STJ11105248
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CAVIN2 antibody (325-425) (STJ11105248)
详情介绍：
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Caveolae-Associated Protein 2 (325-425) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAVIN2
Gene ID: 8436
Uniprot ID: CAVN2_HUMAN
Immunogen Region: 325-425
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 325-425 of human CAVIN2 (NP_004648.1).
Immunogen Sequence: PNDQEEESFAEGHSEASLAS ALVEGEIAEEAAEKATSRGS NSGMDSNIDLTIVEDEEEES VALEQAQKVRYEGSYALTSE EAERSDGDPVQPAVLQVHQT S
Tissue Specificity Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
Post Translational Modifications Phosphorylated on Ser residues.
Function Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae.
Protein Name Caveolae-Associated Protein 2
Cavin-2
Ps-P68
Phosphatidylserine-Binding Protein
Serum Deprivation-Response Protein
Cellular Localisation Cytoplasm
Cytosol
Membrane
Caveola
Localizes In The Caveolae In A Caveolin-Dependent Manner
Alternative Antibody Names Anti-Caveolae-Associated Protein 2 antibody
Anti-Cavin-2 antibody
Anti-Ps-P68 antibody
Anti-Phosphatidylserine-Binding Protein antibody
Anti-Serum Deprivation-Response Protein antibody
Anti-CAVIN2 antibody
Anti-SDPR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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