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  • 产品名称：Anti-CIAO1 antibody (1-339) (STJ29494)

  • 产品型号：STJ29494
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CIAO1 antibody (1-339) (STJ29494)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CIAO1 (1-339) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CIAO1
Gene ID: 9391
Uniprot ID: CIAO1_HUMAN
Immunogen Region: 1-339
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human CIAO1 (NP_004795.1).
Immunogen Sequence: MKDSLVLLGRVPAHPDSRCW FLAWNPAGTLLASCGGDRRI RIWGTEGDSWICKSVLSEGH QRTVRKVAWSPCGNYLASAS FDATTCIWKKNQDDFECVTT LEGHENEVKSVAWAPSGNLL ATCSRDKSVWVWEVDEEDEY ECVSVLNSHTQDVKHVVWHP SQELLASASYDDTVKLYREE EDDWVCCATLEGHESTVWSL AFDPSGQRLASCSDDRTVRI WRQYLPGNEQGVACSGSDP
Function Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Protein Name Probable Cytosolic Iron-Sulfur Protein Assembly Protein Ciao1
Wd Repeat-Containing Protein 39
Database Links Reactome: R-HSA-2564830
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Probable Cytosolic Iron-Sulfur Protein Assembly Protein Ciao1 antibody
Anti-Wd Repeat-Containing Protein 39 antibody
Anti-CIAO1 antibody
Anti-CIA1 antibody
Anti-WDR39 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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