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  • 产品名称：Anti-CLDN10 antibody (179-228 aa) (STJ92309)

  • 产品型号：STJ92309
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CLDN10 antibody (179-228 aa) (STJ92309)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Claudin-10 (179-228 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLDN10
Gene ID: 9071
Uniprot ID: CLD10_HUMAN
Immunogen Region: 179-228 aa
Specificity: Claudin-10 Polyclonal Antibody detects endogenous levels of Claudin-10 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Claudin 10 at the amino acid range 179-228
Function Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores.isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function.
Protein Name Claudin-10
Oligodendrocyte-Specific Protein-Like
Osp-Like
Database Links Reactome: R-HSA-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Claudin-10 antibody
Anti-Oligodendrocyte-Specific Protein-Like antibody
Anti-Osp-Like antibody
Anti-CLDN10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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