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  • 产品名称：Anti-CLDN15 antibody (66-116 aa) (STJ198193)

  • 产品型号：STJ198193
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CLDN15 antibody (66-116 aa) (STJ198193)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Claudin-15 (66-116 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLDN15
Gene ID: 24146
Uniprot ID: CLD15_HUMAN
Immunogen Region: 66-116 aa
Specificity: This antibody detects endogenous levels of human CLD15
Immunogen: Synthesized peptide derived from the human CLD15 at the amino acid range 66-116
Post Translational Modifications Palmitoylated.
Function Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na(+), Li(+) and K(+) ions, but selects against Cl(-) ions. Plays an important role in paracellular Na(+) transport in the intestine and in Na(+) homeostasis. Required for normal Na(+)-dependent intestinal nutrient uptake.
Protein Name Claudin-15
Database Links Reactome: R-HSA-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Multi-Pass Membrane Protein
Tight Junctions Form Continuous Circumferential Cell-Cell Contacts At The Borders Of Apical And Lateral Cell Membranes That Seal The Intercellular Space And Show Up As Strand-Like Structures In Electron Microscopy
Alternative Antibody Names Anti-Claudin-15 antibody
Anti-CLDN15 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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