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  • 产品名称：Anti-CCDC120 antibody (STJA0007659)

  • 产品型号：STJA0007659
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CCDC120 antibody (STJA0007659)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Coiled-coil domain-containing protein 120 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCDC120
Gene ID: 90060
Uniprot ID: CC120_HUMAN
Specificity: This antibody detects endogenous levels of CCDC120 at Human
Immunogen: Synthesized peptide derived from human CCDC120
Function Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells. Together with CCDC68, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly. Recruits NIN and CEP170 to centrosomes. Also required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth.
Protein Name Coiled-Coil Domain-Containing Protein 120
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Cell Projection
Neuron Projection
Growth Cone
Endosome
Localizes To The Subdistal Appendages Of Mother Centrioles And Proximal Ends Of Both Centrioles In Interphase Cells
Recruited To Subdistal Appendages By Odf2
In Differentiating Neuroblastoma Cells
Colocalizes With Cyth2 In Both Neurite Shaft And Growth Cone Areas
Partially Colocalizes With Endosomes Along Neurites In Differentiating Neuroblastoma Cells
Alternative Antibody Names Anti-Coiled-Coil Domain-Containing Protein 120 antibody
Anti-CCDC120 antibody
Anti-JM11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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