产品详情
简单介绍:
Anti-CCL14 antibody (44-93 aa) (STJ98768)
详情介绍:
Host: | Rabbit |
Applications: | IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-C-C motif chemokine 14 (44-93 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC-P 1:50-200 ELISA 1:10000-20000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCL14 |
Gene ID: | 6358 |
Uniprot ID: | CCL14_HUMAN |
Immunogen Region: | 44-93 aa |
Specificity: | The antibody detects endogenous CCL14 |
Immunogen: | Synthetic peptide from the human protein at the amino acid range 44-93 |
Post Translational Modifications | The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood. HCC-1(1-74), but not HCC-1(3-74) and HCC-1(4-74), is partially O-glycosylated.the O-linked glycan consists of one Gal-GalNAc disaccharide, further modified by two N-acetylneuraminic acids. |
Function | Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induces intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. |
Protein Name | C-C Motif Chemokine 14 Chemokine Cc-1/Cc-3 Hcc-1/Hcc-3 Hcc-1(1-74 Ncc-2 Small-Inducible Cytokine A14 Cleaved Into - Hcc-1(3-74 - Hcc-1(4-74 - Hcc-1(9-74 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-C Motif Chemokine 14 antibody Anti-Chemokine Cc-1/Cc-3 antibody Anti-Hcc-1/Hcc-3 antibody Anti-Hcc-1(1-74 antibody Anti-Ncc-2 antibody Anti-Small-Inducible Cytokine A14 Cleaved Into - Hcc-1(3-74 - Hcc-1(4-74 - Hcc-1(9-74 antibody Anti-CCL14 antibody Anti-NCC2 antibody Anti-SCYA14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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