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  • 产品名称：Anti-Cleaved-F8-Arg759, Heavy Chain antibody (759-760) (STJA0005864)

  • 产品型号：STJA0005864
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-Cleaved-F8-Arg759, Heavy Chain antibody (759-760) (STJA0005864)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Coagulation factor VIII-Arg759, Heavy Chain (759-760) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: F8
Gene ID: 2157
Uniprot ID: FA8_HUMAN
Immunogen Region: 759-760
Specificity: This antibody detects endogenous levels of Human, Mouse FA8A (heavy chain 92k, Cleaved-Arg759, protein was cleaved amino acid sequence between 759-760 )
Immunogen: Synthesized peptide derived from human FA8A (heavy chain 92k, Cleaved-Arg759)
Post Translational Modifications Sulfation on Tyr-1699 is essential for binding vWF. Proteolytically cleaved by cathepsin CTSG to produce a partially activated form.
Function Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.
Protein Name Coagulation Factor Viii
Antihemophilic Factor
Ahf
Procoagulant Component Cleaved Into - Factor Viiia Heavy Chain - 200 Kda Isoform - Factor Viiia Heavy Chain - 92 Kda Isoform - Factor Viii B Chain - Factor Viiia Light Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140837
Reactome: R-HSA-140875
Reactome: R-HSA-163841
Reactome: R-HSA-204005
Reactome: R-HSA-5694530
Reactome: R-HSA-9672383
Reactome: R-HSA-9672387
Reactome: R-HSA-9672391
Reactome: R-HSA-9672393
Reactome: R-HSA-9672395
Reactome: R-HSA-9672396
Reactome: R-HSA-9672397
Reactome: R-HSA-9673202
Reactome: R-HSA-9674519
Cellular Localisation Secreted
Extracellular Space
Alternative Antibody Names Anti-Coagulation Factor Viii antibody
Anti-Antihemophilic Factor antibody
Anti-Ahf antibody
Anti-Procoagulant Component Cleaved Into - Factor Viiia Heavy Chain - 200 Kda Isoform - Factor Viiia Heavy Chain - 92 Kda Isoform - Factor Viii B Chain - Factor Viiia Light Chain antibody
Anti-F8 antibody
Anti-F8C antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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