产品详情
简单介绍:
Human TITF1 (Thyroid Transcription Factor 1) Sandwich ELISA Kit (STJE0012614)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.062ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This TITF1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | NKX2-1 |
Gene ID: | 7080 |
Uniprot ID: | NKX21_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Thyroid and lung. |
Post Translational Modifications | Phosphorylated on serine residues by STK3/MST2. |
Function | Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1. |
Protein Name | Homeobox Protein Nkx-2.1 Homeobox Protein Nk-2 Homolog A Thyroid Nuclear Factor 1 Thyroid Transcription Factor 1 Ttf-1 Thyroid-Specific Enhancer-Binding Protein T/Ebp |
Database Links | |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Homeobox Protein Nkx-2.1 ELISA kit Homeobox Protein Nk-2 Homolog A ELISA kit Thyroid Nuclear Factor 1 ELISA kit Thyroid Transcription Factor 1 ELISA kit Ttf-1 ELISA kit Thyroid-Specific Enhancer-Binding Protein ELISA kit T/Ebp ELISA kit NKX2-1 ELISA kit NKX2A ELISA kit TITF1 ELISA kit TTF1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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