产品详情
简单介绍:
Human TPM2 (Tropomyosin 2 Beta) Sandwich ELISA Kit Ready-To-Use (STJE0019148)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.247ng/mL |
Detection Limit: | 0.625-40ng/mL |
Short Description: | This TPM2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | TPM2 |
Gene ID: | 7169 |
Uniprot ID: | TPM2_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Present in primary breast cancer tissue, absent from normal breast tissue. |
Post Translational Modifications | Phosphorylated on Ser-61 by PIK3CG. Phosphorylation on Ser-61 is required for ADRB2 internalization. |
Function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. |
Protein Name | Tropomyosin Beta Chain Beta-Tropomyosin Tropomyosin-2 |
Database Links | Reactome: R-HSA-390522 Reactome: R-HSA-445355 |
Cellular Localisation | Cytoplasm Cytoskeleton Associates With F-Actin Stress Fibers |
Alternative ELISA Names | Tropomyosin Beta Chain ELISA kit Beta-Tropomyosin ELISA kit Tropomyosin-2 ELISA kit TPM2 ELISA kit TMSB ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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