产品详情
简单介绍:
Human TRPM7 (Transient Receptor Potential Cation Channel Subfamily M, Member 7) Sandwich ELISA Kit Ready-To-Use (STJE0019210)
详情介绍:
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 33pg/mL |
| Detection Limit: | 78.1-5000pg/mL |
| Short Description: | This TRPM7 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | TRPM7 |
| Gene ID: | 54822 |
| Uniprot ID: | TRPM7_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Autophosphorylated. |
| Function | Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily M Member 7 Channel-Kinase 1 Long Transient Receptor Potential Channel 7 Ltrpc-7 Ltrpc7 |
| Database Links | Reactome: R-HSA-3295583 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein |
| Alternative ELISA Names | Transient Receptor Potential Cation Channel Subfamily M Member 7 ELISA kit Channel-Kinase 1 ELISA kit Long Transient Receptor Potential Channel 7 ELISA kit Ltrpc-7 ELISA kit Ltrpc7 ELISA kit TRPM7 ELISA kit CHAK1 ELISA kit LTRPC7 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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