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  • 产品名称：Anti-CNTNAP1 antibody (20-300) (STJ112098)

  • 产品型号：STJ112098
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CNTNAP1 antibody (20-300) (STJ112098)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CNTNAP1 (20-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTNAP1
Gene ID: 8506
Uniprot ID: CNTP1_HUMAN
Immunogen Region: 20-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human Caspr1 (NP_003623.1).
Immunogen Sequence: WGYYGCDEELVGPLYARSLG ASSYYSLLTAPRFARLHGIS GWSPRIGDPNPWLQIDLMKK HRIRAVATQGSFNSWDWVTR YMLLYGDRVDSWTPFYQRGH NSTFFGNVNESAVVRHDLHF HFTARYIRIVPLAWNPRGKI GLRLGLYGCPYKADILYFDG DDAISYRFPRGVSRSLWDVF AFSFKTEEKDGLLLHAEGAQ GDYVTLELEGAHLLLHMSLG SSPIQPRPGHTTVSAGGVL
Tissue Specificity Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis.
Function Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Protein Name Contactin-Associated Protein 1
Caspr
Caspr1
Neurexin Iv
Neurexin-4
P190
Database Links Reactome: R-HSA-447043
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Paranodal Septate Junction
Alternative Antibody Names Anti-Contactin-Associated Protein 1 antibody
Anti-Caspr antibody
Anti-Caspr1 antibody
Anti-Neurexin Iv antibody
Anti-Neurexin-4 antibody
Anti-P190 antibody
Anti-CNTNAP1 antibody
Anti-CASPR antibody
Anti-NRXN4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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