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  • 产品名称：Human UBE2A (Ubiquitin Conjugating Enzyme E2A) Sandwich ELISA Kit Ready-To-Use (STJE0019281)

  • 产品型号：STJE0019281
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human UBE2A (Ubiquitin Conjugating Enzyme E2A) Sandwich ELISA Kit Ready-To-Use (STJE0019281)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.081ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This UBE2A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: UBE2A
Gene ID: 7319
Uniprot ID: UBE2A_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation at Ser-120 by CDK9 increases activity towards histone H2B.
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Protein Name Ubiquitin-Conjugating Enzyme E2 A
E2 Ubiquitin-Conjugating Enzyme A
Rad6 Homolog A
Hr6a
Hhr6a
Ubiquitin Carrier Protein A
Ubiquitin-Protein Ligase A
Database Links Reactome: R-HSA-8866652
Reactome: R-HSA-8866654
Reactome: R-HSA-983168
Cellular Localisation
Alternative ELISA Names Ubiquitin-Conjugating Enzyme E2 A ELISA kit
E2 Ubiquitin-Conjugating Enzyme A ELISA kit
Rad6 Homolog A ELISA kit
Hr6a ELISA kit
Hhr6a ELISA kit
Ubiquitin Carrier Protein A ELISA kit
Ubiquitin-Protein Ligase A ELISA kit
UBE2A ELISA kit
RAD6A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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