产品详情
简单介绍:
Human VAChT (Vesicular Acetylcholine Transporter) Sandwich ELISA Kit (STJE0012964)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.117ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This VAChT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | SLC18A3 |
Gene ID: | 6572 |
Uniprot ID: | VACHT_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Peripheral and central cholinergic nervous systems. |
Post Translational Modifications | |
Function | Electrogenic antiporter that exchanges one cholinergic neurotransmitter, acetylcholine or choline, with two intravesicular protons across the membrane of synaptic vesicles. Uses the electrochemical proton gradient established by the V-type proton-pump ATPase to store neurotransmitters inside the vesicles prior to their release via exocytosis. Determines cholinergic vesicular quantal size at presynaptic nerve terminals in developing neuro-muscular junctions with an impact on motor neuron differentiation and innervation pattern. Part of forebrain cholinergic system, regulates hippocampal synapse transmissions that underlie spatial memory formation. Can transport serotonin. |
Protein Name | Vesicular Acetylcholine Transporter Vacht Solute Carrier Family 18 Member 3 |
Database Links | Reactome: R-HSA-264642 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
Cellular Localisation | Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Vesicular Acetylcholine Transporter ELISA kit Vacht ELISA kit Solute Carrier Family 18 Member 3 ELISA kit SLC18A3 ELISA kit VACHT ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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