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  • 产品名称：Human VAMP2 (Vesicle Associated Membrane Protein 2) Sandwich ELISA Kit Ready-To-Use (STJE0019353)

  • 产品型号：STJE0019353
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human VAMP2 (Vesicle Associated Membrane Protein 2) Sandwich ELISA Kit Ready-To-Use (STJE0019353)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.057ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This VAMP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: VAMP2
Gene ID: 6844
Uniprot ID: VAMP2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Nervous system and skeletal muscle.
Post Translational Modifications Phosphorylated by PRKCZ in vitro and this phosphorylation is increased in the presence of WDFY2. (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type B (BoNT/B, botB) which hydrolyzes the 76-Gln-|-Phe-77 bond and probably inhibits neurotransmitter release. (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type D (BoNT/D, botD) which probably hydrolyzes the 59-Lys-|-Leu-60 bond and inhibits neurotransmitter release. Note that humans are not known to be infected by C.botulinum type D. (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type F (BoNT/F, botF) which hydrolyzes the 58-Gln-|-Lys-59 bond and probably inhibits neurotransmitter release. (Microbial infection) Targeted and hydrolyzed by C.tetani tetanus toxin (tetX) which hydrolyzes the 76-Gln-|-Phe-77 bond and probably inhibits neurotransmitter release.
Function Involved in the targeting and/or fusion of transport vesicles to their target membrane. Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
Protein Name Vesicle-Associated Membrane Protein 2
Vamp-2
Synaptobrevin-2
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-181429
Reactome: R-HSA-181430
Reactome: R-HSA-199992
Reactome: R-HSA-210500
Reactome: R-HSA-212676
Reactome: R-HSA-264642
Reactome: R-HSA-264876
Reactome: R-HSA-422356
Reactome: R-HSA-432720
Reactome: R-HSA-432722
Reactome: R-HSA-449836
Reactome: R-HSA-5250955
Reactome: R-HSA-5250958
Reactome: R-HSA-5250981
Reactome: R-HSA-5250982
Reactome: R-HSA-5250989
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-888590
Reactome: R-HSA-9609523
Reactome: R-HSA-9662360
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Single-Pass Type Iv Membrane Protein
Cell Membrane
Colocalizes With Prkcz And Wdfy2 In Intracellular Vesicles
Alternative ELISA Names Vesicle-Associated Membrane Protein 2 ELISA kit
Vamp-2 ELISA kit
Synaptobrevin-2 ELISA kit
VAMP2 ELISA kit
SYB2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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