产品详情
简单介绍:
Human VAMP3 (Vesicle-Associated Membrane Protein 3) Sandwich ELISA Kit (STJE0012966)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 30pg/mL |
Detection Limit: | 78.125-5000pg/mL |
Short Description: | This VAMP3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | VAMP3 |
Gene ID: | 9341 |
Uniprot ID: | VAMP3_HUMAN |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Ubiquitinated by RNF167 at Lys-66, Lys-68 and Lys-77, regulating the recycling endosome pathway. (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type B (BoNT/B, botB) which hydrolyzes the 59-Gln-|-Phe-60 bond and probably inhibits neurotransmitter release. (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type D (BoNT/D, botD) which hydrolyzes the 42-Lys-|-Leu-43 bond and probably inhibits neurotransmitter release. Note that humans are not known to be infected by C.botulinum type D. (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type F (BoNT/F, botF) which hydrolyzes the 41-Gln-|-Lys-42 bond and probably inhibits neurotransmitter release. |
Function | SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. |
Protein Name | Vesicle-Associated Membrane Protein 3 Vamp-3 Cellubrevin Ceb Synaptobrevin-3 |
Database Links | Reactome: R-HSA-1236974 Reactome: R-HSA-6811440 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013404 Reactome: R-HSA-9013405 Reactome: R-HSA-9013406 Reactome: R-HSA-9013407 Reactome: R-HSA-9013408 Reactome: R-HSA-9013409 Reactome: R-HSA-9013423 Reactome: R-HSA-9035034 |
Cellular Localisation | Early Endosome Membrane Single-Pass Type Iv Membrane Protein Recycling Endosome Membrane Single-Pass Type I Membrane Protein Synapse Synaptosome |
Alternative ELISA Names | Vesicle-Associated Membrane Protein 3 ELISA kit Vamp-3 ELISA kit Cellubrevin ELISA kit Ceb ELISA kit Synaptobrevin-3 ELISA kit VAMP3 ELISA kit SYB3 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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