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  • 产品名称：Anti-COQ2 antibody (160-210 aa) (STJ194292)

  • 产品型号：STJ194292
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-COQ2 antibody (160-210 aa) (STJ194292)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-4-hydroxybenzoate polyprenyltransferase, mitochondrial (160-210 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COQ2
Gene ID: 27235
Uniprot ID: COQ2_HUMAN
Immunogen Region: 160-210 aa
Specificity: This antibody detects endogenous levels of COQ2 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human COQ2 at the amino acid range 160-210
Function Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis. Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl donor (such as all-trans-decaprenyl diphosphate). The length of the polyprenyl side chain varies depending on the species, in humans, the side chain is comprised of 10 isoprenyls (decaprenyl) producing CoQ10 (also known as ubiquinone), whereas rodents predominantly generate CoQ9. However, this specificity is not complete, human tissues have low amounts of CoQ9 and rodent organs contain some CoQ10. Plays a central role in the biosynthesis of CoQ10. CoQ10 is a vital molecule that transports electrons from mitochondrial respiratory chain complexes. CoQs also function as cofactors for uncoupling protein and play a role as regulators of the extracellularly-induced ceramide-dependent apoptotic pathway. Regulates mitochondrial permeability transition pore (mPTP) opening and ROS production (pivotal events in cell death) in a tissue specific manner.
Protein Name 4-Hydroxybenzoate Polyprenyltransferase - Mitochondrial
4-Hb Polyprenyltransferase
4-Hydroxybenzoate Decaprenyltransferase
Coq2 Homolog
Hcoq2
Para-Hydroxybenzoate--Polyprenyltransferase
Phb -Ppt
Phb -Polyprenyltransferase
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-2142789
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Matrix Side
Alternative Antibody Names Anti-4-Hydroxybenzoate Polyprenyltransferase - Mitochondrial antibody
Anti-4-Hb Polyprenyltransferase antibody
Anti-4-Hydroxybenzoate Decaprenyltransferase antibody
Anti-Coq2 Homolog antibody
Anti-Hcoq2 antibody
Anti-Para-Hydroxybenzoate--Polyprenyltransferase antibody
Anti-Phb -Ppt antibody
Anti-Phb -Polyprenyltransferase antibody
Anti-COQ2 antibody
Anti-CL640 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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