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  • 产品名称：Anti-CORO1A antibody (150-230 aa) (STJ92426)

  • 产品型号：STJ92426
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CORO1A antibody (150-230 aa) (STJ92426)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Coronin-1A (150-230 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CORO1A
Gene ID: 11151
Uniprot ID: COR1A_HUMAN
Immunogen Region: 150-230 aa
Specificity: Coronin 1A Polyclonal Antibody detects endogenous levels of Coronin 1A protein.
Immunogen: Synthesized peptide derived from Coronin 1A at the amino acid range 150-230
Post Translational Modifications phosphorylation at Thr-412 by PKC strongly down-regulates the association with actin. Polyubiquitinated by RNF128 with 'Lys-48'-linked chains, leading to proteasomal degradation.
Function May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Protein Name Coronin-1a
Coronin-Like Protein A
Clipin-A
Coronin-Like Protein P57
Tryptophan Aspartate-Containing Coat Protein
Taco
Database Links Reactome: R-HSA-9636383
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Cytoplasmic Vesicle
Phagosome Membrane
In Non-Infected Macrophages
Associated With The Cortical Microtubule Network
In Mycobacteria-Infected Macrophages
Becomes Progressively Relocalized And Retained Around The Mycobacterial Phagosomes
Retention On The Phagosomal Membrane Is Strictly Dependent On Mycobacterial Viability And Not Due To Impaired Acidification
Alternative Antibody Names Anti-Coronin-1a antibody
Anti-Coronin-Like Protein A antibody
Anti-Clipin-A antibody
Anti-Coronin-Like Protein P57 antibody
Anti-Tryptophan Aspartate-Containing Coat Protein antibody
Anti-Taco antibody
Anti-CORO1A antibody
Anti-CORO1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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