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  • 产品名称：Anti-COX4I1 antibody [6C8] {Biotin} (STJA0006021)

  • 产品型号：STJA0006021
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-COX4I1 antibody [6C8] {Biotin} (STJA0006021)
详情介绍：
Host: Mouse
Applications: WB/IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Cytochrome c oxidase subunit 4 isoform 1, mitochondrial is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: 6C8
Conjugation: Biotin
Isotype: IgG1
Formulation: Liquid in PBS pH7.4, containing 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was purified using affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: Optimal working dilutions should be determined experimentally by the investigator Suggested starting dilutions are as follows: WB 1:1000-3000 IHC 1:50-300
Storage Instruction: Stable for one year at-15°C to-25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezi
Gene Symbol: COX4I1
Gene ID: 1327
Uniprot ID: COX41_HUMAN
Specificity: COX IV Monoclonal Antibody (6C8) Biotin conjugated specially designed for your WB or IHC analysis.
Tissue Specificity Ubiquitous.
Function Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Protein Name Cytochrome C Oxidase Subunit 4 Isoform 1 - Mitochondrial
Cytochrome C Oxidase Polypeptide Iv
Cytochrome C Oxidase Subunit Iv Isoform 1
Cox Iv-1
Database Links Reactome: R-HSA-5628897
Reactome: R-HSA-611105
Reactome: R-HSA-9707564
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Cytochrome C Oxidase Subunit 4 Isoform 1 - Mitochondrial antibody
Anti-Cytochrome C Oxidase Polypeptide Iv antibody
Anti-Cytochrome C Oxidase Subunit Iv Isoform 1 antibody
Anti-Cox Iv-1 antibody
Anti-COX4I1 antibody
Anti-COX4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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