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  • 产品名称：Anti-COX6A1 antibody (25-109) (STJ26481)

  • 产品型号：STJ26481
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-COX6A1 antibody (25-109) (STJ26481)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-COX6A1 (25-109) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
IHC-P 1:20-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COX6A1
Gene ID: 1337
Uniprot ID: CX6A1_HUMAN
Immunogen Region: 25-109
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-109 of human COX6A1 (NP_004364.2).
Immunogen Sequence: SSGAHGEEGSARMWKTLTFF VALPGVAVSMLNVYLKSHHG EHERPEFIAYPHLRIRTKPF PWGDGNHTLFHNPHVNPLPT GYEDE
Function Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Protein Name Cytochrome C Oxidase Subunit 6a1 - Mitochondrial
Cytochrome C Oxidase Polypeptide Via-Liver
Cytochrome C Oxidase Subunit Via-Liver
Cox Via-L
Database Links Reactome: R-HSA-5628897
Reactome: R-HSA-611105
Reactome: R-HSA-9707564
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Cytochrome C Oxidase Subunit 6a1 - Mitochondrial antibody
Anti-Cytochrome C Oxidase Polypeptide Via-Liver antibody
Anti-Cytochrome C Oxidase Subunit Via-Liver antibody
Anti-Cox Via-L antibody
Anti-COX6A1 antibody
Anti-COX6AL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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