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  • 产品名称：Anti-CPNE1 antibody (120-220) (STJ118194)

  • 产品型号：STJ118194
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CPNE1 antibody (120-220) (STJ118194)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CPNE1 (120-220) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CPNE1
Gene ID: 8904
Uniprot ID: CPNE1_HUMAN
Immunogen Region: 120-220
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-220 of human CPNE1 (NP_003906.2).
Immunogen Sequence: MLKPGKPAGRGTITVSAQEL KDNRVVTMEVEARNLDKKDF LGKSDPFLEFFRQGDGKWHL VYRSEVIKNNLNPTWKRFSV PVQHFCGGNPSTPIQVQCSD Y
Tissue Specificity Expressed in neutrophils (at protein level). Widely expressed. Expressed in the brain. Expressed in neutrophil precursors from bone marrow and peripheral blood.
Function Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation.induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit. Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL.
Protein Name Copine-1
Chromobindin 17
Copine I
Database Links Reactome: R-HSA-1483206
Reactome: R-HSA-6798695
Cellular Localisation Nucleus
Cytoplasm
Cell Membrane
Translocates To The Cell Membrane In A Calcium-Dependent Manner
Alternative Antibody Names Anti-Copine-1 antibody
Anti-Chromobindin 17 antibody
Anti-Copine I antibody
Anti-CPNE1 antibody
Anti-CPN1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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