产品详情
简单介绍:
Mouse ADRb1 (Adrenergic Receptor Beta 1) Sandwich ELISA Kit (STJE0006960)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.059ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This ADRb1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Adrb1 |
Gene ID: | 11554 |
Uniprot ID: | ADRB1_MOUSE |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | In brain, expressed by glutamatergic and GABAergic neurons of the dorsal pons (at protein level). |
Post Translational Modifications | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
Protein Name | Beta-1 Adrenergic Receptor Beta-1 Adrenoreceptor Beta-1 Adrenoceptor |
Database Links | Reactome: R-MMU-390696 Reactome: -MMU-418555 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Early Endosome Colocalizes With Rapgef2 At The Plasma Membrane Found In The Golgi Upon Gopc Overexpression |
Alternative ELISA Names | Beta-1 Adrenergic Receptor ELISA kit Beta-1 Adrenoreceptor ELISA kit Beta-1 Adrenoceptor ELISA kit Adrb1 ELISA kit Adrb1r ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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