产品详情
简单介绍:
Mouse ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) Sandwich ELISA Kit Ready-To-Use (STJE0013697)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.043ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This ARPC4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Arpc4 |
Gene ID: | 68089 |
Uniprot ID: | ARPC4_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs). |
Protein Name | Actin-Related Protein 2/3 Complex Subunit 4 Arp2/3 Complex 20 Kda Subunit P20-Arc |
Database Links | Reactome: R-MMU-2029482 Reactome: -MMU-3928662 Reactome: -MMU-5663213 Reactome: -MMU-8856828 |
Cellular Localisation | Cytoplasm Cytoskeleton Cell Projection Nucleus |
Alternative ELISA Names | Actin-Related Protein 2/3 Complex Subunit 4 ELISA kit Arp2/3 Complex 20 Kda Subunit ELISA kit P20-Arc ELISA kit Arpc4 ELISA kit Arc20 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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