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  • 产品名称：Anti-CTDP1 antibody (73-123 aa) (STJ193715)

  • 产品型号：STJ193715
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CTDP1 antibody (73-123 aa) (STJ193715)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNA polymerase II subunit A C-terminal domain phosphatase (73-123 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTDP1
Gene ID: 9150
Uniprot ID: CTDP1_HUMAN
Immunogen Region: 73-123 aa
Specificity: This antibody detects endogenous levels of CTDP1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human CTDP1 at the amino acid range 73-123
Post Translational Modifications Phosphorylated. In the presence of TFIIF, the phosphorylated form has an increased CTD phosphatase activity. The phosphorylation is required for the physical interaction with GTF2F1.
Function Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.
Protein Name Rna Polymerase Ii Subunit A C-Terminal Domain Phosphatase
Tfiif-Associating Ctd Phosphatase
Database Links Reactome: R-HSA-112382
Reactome: R-HSA-113418
Reactome: R-HSA-167152
Reactome: R-HSA-167158
Reactome: R-HSA-167200
Reactome: R-HSA-167238
Reactome: R-HSA-167242
Reactome: R-HSA-167243
Reactome: R-HSA-167246
Reactome: R-HSA-167287
Reactome: R-HSA-167290
Reactome: R-HSA-674695
Reactome: R-HSA-6796648
Reactome: R-HSA-75955
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle Pole
Midbody
Found At Centrosomes In Prometaphase
At Spindle And Spindle Poles In Metaphase And At Spindle Midzone And Midbody In Anaphase And Telophase-G1 Respectively
Alternative Antibody Names Anti-Rna Polymerase Ii Subunit A C-Terminal Domain Phosphatase antibody
Anti-Tfiif-Associating Ctd Phosphatase antibody
Anti-CTDP1 antibody
Anti-FCP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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