产品详情
查看大图

  • 产品名称：Anti-CD19 antibody (422-433) (STJ72998)

  • 产品型号：STJ72998-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-CD19 antibody (422-433) (STJ72998)
详情介绍：
Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CD19 (422-433) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CD19
Gene ID: 930
Uniprot ID: CD19_HUMAN
Immunogen Region: 422-433
Accession Number: NP_001171569.1; NP_001761.3
Specificity: This antibody is expected to recognize both reported isoforms (NP_001171569.1; NP_001761.3).
Immunogen Sequence: ENDSNLGQDQLS
Post Translational Modifications Phosphorylated on tyrosine following B-cell activation. Phosphorylated on tyrosine residues by LYN. Tyrosine residues are phosphorylated sequentially after activation of the B cell receptor. Phosphorylation of Tyr-531 is extremely rapid, followed by phosphorylation at Tyr-409. In contrast, phosphorylation of Tyr-500 appears more slowly and is more transient, returning rapidly to basal levels.
Function Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
Protein Name B-Lymphocyte Antigen Cd19
B-Lymphocyte Surface Antigen B4
Differentiation Antigen Cd19
T-Cell Surface Antigen Leu-12
Cd Antigen Cd19
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-198933
Reactome: R-HSA-2219530
Reactome: R-HSA-6811558
Reactome: R-HSA-977606
Reactome: R-HSA-983695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Alternative Antibody Names Anti-B-Lymphocyte Antigen Cd19 antibody
Anti-B-Lymphocyte Surface Antigen B4 antibody
Anti-Differentiation Antigen Cd19 antibody
Anti-T-Cell Surface Antigen Leu-12 antibody
Anti-Cd Antigen Cd19 antibody
Anti-CD19 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号