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  • 产品名称：Anti-CTSE antibody (132-244) [S4701RM] (STJ11104701)

  • 产品型号：STJ11104701
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CTSE antibody (132-244) [S4701RM] (STJ11104701)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Cathepsin E Cleaved Into-Cathepsin E Form I-Cathepsin E Form Ii (132-244) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4701RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTSE
Gene ID: 1510
Uniprot ID: CATE_HUMAN
Immunogen Region: 132-244
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 132-244 of human Cathepsin E (CTSE) (NP_001901.1).
Immunogen Sequence: GQSFSIQYGTGSLSGIIGAD QVSVEGLTVVGQQFGESVTE PGQTFVDAEFDGILGLGYPS LAVGGVTPVFDNMMAQNLVD LPMFSVYMSSNPEGGAGSEL IFGGYDHSHFSGS
Tissue Specificity Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.
Post Translational Modifications Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57.
Function May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
Protein Name Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii
Database Links Reactome: R-HSA-2132295
Cellular Localisation Endosome
The Proenzyme Is Localized To The Endoplasmic Reticulum And Golgi Apparatus
While The Mature Enzyme Is Localized To The Endosome
Alternative Antibody Names Anti-Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii antibody
Anti-CTSE antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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