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  • 产品名称：Anti-CLCN7 antibody (626-805) (STJ114296)

  • 产品型号：STJ114296
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CLCN7 antibody (626-805) (STJ114296)
详情介绍：
Host: Rabbit
Applications: IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CLCN7 (626-805) is suitable for use in Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IF 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLCN7
Gene ID: 1186
Uniprot ID: CLCN7_HUMAN
Immunogen Region: 626-805
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 626-805 of human CLCN7 (NP_001278.1).
Immunogen Sequence: TAREVMSTPVTCLRRREKVG VIVDVLSDTASNHNGFPVVE HADDTQPARLQGLILRSQLI VLLKHKVFVERSNLGLVQRR LRLKDFRDAYPRFPPIQSIH VSQDERECTMDLSEFMNPSP YTVPQEASLPRVFKLFRALG LRHLVVVDNRNQVVGLVTRK DLARYRLGKRGLEELSLAQT
Tissue Specificity Brain and kidney.
Function Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.
Protein Name H(+/Cl(- Exchange Transporter 7
Chloride Channel 7 Alpha Subunit
Chloride Channel Protein 7
Clc-7
Database Links Reactome: R-HSA-2672351
Cellular Localisation Lysosome Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-H(+/Cl(- Exchange Transporter 7 antibody
Anti-Chloride Channel 7 Alpha Subunit antibody
Anti-Chloride Channel Protein 7 antibody
Anti-Clc-7 antibody
Anti-CLCN7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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