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  • 产品名称：Human WNT1 (Wingless Type MMTV Integration Site Family, Member 1) Sandwich ELISA Kit (STJE0013091)

  • 产品型号：STJE0013091
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human WNT1 (Wingless Type MMTV Integration Site Family, Member 1) Sandwich ELISA Kit (STJE0013091)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This WNT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: WNT1
Gene ID: 7471
Uniprot ID: WNT1_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Palmitoleoylation is required for efficient binding to frizzled receptors. Palmitoleoylation is necessary for proper trafficking to cell surface (Probable). Depalmitoleoylated by NOTUM, leading to inhibit Wnt signaling pathway.
Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.
Protein Name Proto-Oncogene Wnt-1
Proto-Oncogene Int-1 Homolog
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-3238698
Reactome: R-HSA-373080
Reactome: R-HSA-381340
Reactome: R-HSA-4086400
Reactome: R-HSA-4641262
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative ELISA Names Proto-Oncogene Wnt-1 ELISA kit
Proto-Oncogene Int-1 Homolog ELISA kit
WNT1 ELISA kit
INT1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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