产品详情
简单介绍:
Anti-CP antibody (680-790) (STJ115616)
详情介绍:
Host: | Rabbit |
Applications: | IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Ceruloplasmin (680-790) is suitable for use in Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CP |
Gene ID: | 1356 |
Uniprot ID: | CERU_HUMAN |
Immunogen Region: | 680-790 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 680-790 of human Ceruloplasmin (NP_000087.1). |
Immunogen Sequence: | QTSLTLHMWPDTEGTFNVEC LTTDHYTGGMKQKYTVNQCR RQSEDSTFYLGERTYYIAAV EVEWDYSPQREWEKELHHLQ EQNVSNAFLDKGEFYIGSKY KKVVYRQYTDS |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Function | Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense. |
Protein Name | Ceruloplasmin Ferroxidase |
Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-425410 Reactome: R-HSA-5619049 Reactome: R-HSA-5619060 Reactome: R-HSA-8957275 Reactome: R-HSA-917937 |
Cellular Localisation | Secreted Colocalizes With Gcp1 In Secretory Intracellular Compartments |
Alternative Antibody Names | Anti-Ceruloplasmin antibody Anti-Ferroxidase antibody Anti-CP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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