产品详情
查看大图

  • 产品名称：Anti-CSNK1G2 antibody (316-415) (STJ29465)

  • 产品型号：STJ29465
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-CSNK1G2 antibody (316-415) (STJ29465)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CSNK1G2 (316-415) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CSNK1G2
Gene ID: 1455
Uniprot ID: KC1G2_HUMAN
Immunogen Region: 316-415
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).
Immunogen Sequence: FDRSGFVFDYEYDWAGKPLP TPIGTVHTDLPSQPQLRDKT QPHSKNQALNSTNGELNADD PTAGHSNAPITAPAEVEVAD ETKCCCFFKRRKRKSLQRHK
Tissue Specificity Testis.
Post Translational Modifications Autophosphorylated. Phosphorylated by aPKC which promotes dissociation from the cell cortex.
Function Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. Involved in regulation of reactive oxygen species (ROS) levels.
Protein Name Casein Kinase I Isoform Gamma-2
Cki-Gamma 2
Database Links Reactome: R-HSA-1660661
Reactome: R-HSA-4641262
Cellular Localisation Cytoplasm
Cell Cortex
Alternative Antibody Names Anti-Casein Kinase I Isoform Gamma-2 antibody
Anti-Cki-Gamma 2 antibody
Anti-CSNK1G2 antibody
Anti-CK1G2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号