产品详情
简单介绍:
Anti-CTBP1 antibody (20-250) (STJ23254)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CTBP1 (20-250) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CTBP1 |
Gene ID: | 1487 |
Uniprot ID: | CTBP1_HUMAN |
Immunogen Region: | 20-250 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human CtBP1 (NP_001319.1). |
Immunogen Sequence: | MNGPLHPRPLVALLDGRDCT VEMPILKDVATVAFCDAQST QEIHEKVLNEAVGALMYHTI TLTREDLEKFKALRIIVRIG SGFDNIDIKSAGDLGIAVCN VPAASVEETADSTLCHILNL YRRATWLHQALREGTRVQSV EQIREVASGAARIRGETLGI IGLGRVGQAVALRAKAFGFN VLFYDPYLSDGVERALGLQR VSTLQDLLFHSDCVTLHCGL NEHNHHLINDF |
Tissue Specificity | Expressed in germinal center B-cells. |
Post Translational Modifications | The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated.when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4. |
Function | Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. |
Protein Name | C-Terminal-Binding Protein 1 Ctbp1 |
Database Links | Reactome: R-HSA-3769402 Reactome: R-HSA-3899300 Reactome: R-HSA-4641265 Reactome: R-HSA-5339700 |
Cellular Localisation | Cytoplasm Nucleus |
Alternative Antibody Names | Anti-C-Terminal-Binding Protein 1 antibody Anti-Ctbp1 antibody Anti-CTBP1 antibody Anti-CTBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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