产品详情
简单介绍:
Mouse C9 (Complement Component 9) Sandwich ELISA Kit Ready-To-Use (STJE0013987)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.19ng/mL |
Detection Limit: | 0.468-30ng/mL |
Short Description: | This C9 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | C9 |
Gene ID: | 12279 |
Uniprot ID: | CO9_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Initially, positions and connectivity of disulfide bonds were based on peptide sequencing done for the human protein. The high-resolution crystal structure for the mouse protein corrected the positions and connectivities of some disulfide bonds. The distance between Cys-55 and Cys-92 in the monomeric mouse protein precludes formation of a disulfide bond, contrary to what is seen in the structure of the human polymeric form of the protein (Probable). |
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. |
Protein Name | Complement Component C9 |
Database Links | Reactome: R-MMU-166665 Reactome: -MMU-977606 |
Cellular Localisation | Secreted Target Cell Membrane Multi-Pass Membrane Protein Secreted As Soluble Monomer Oligomerizes At Target Membranes Forming A Pre-Pore A Conformation Change Then Leads To The Formation Of A 100 Angstrom Diameter Pore |
Alternative ELISA Names | Complement Component C9 ELISA kit C9 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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