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  • 产品名称：Anti-CUX1 antibody (1150-1230 aa) (STJ190132)

  • 产品型号：STJ190132
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CUX1 antibody (1150-1230 aa) (STJ190132)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Homeobox protein cut-like 1 (1150-1230 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CUX1
Gene ID: 1523
Uniprot ID: CUX1_HUMAN
Immunogen Region: 1150-1230 aa
Specificity: CUX1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 1150-1230
Function Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III. Also involved in the control of synaptogenesis. In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor.binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer.may require the basic helix-loop-helix protein TCF4 as a coactivator. CDP/Cux p110: Plays a role in cell cycle progression, in particular at the G1/S transition. As cells progress into S phase, a fraction of CUX1 molecules is proteolytically processed into N-terminally truncated proteins of 110 kDa. While CUX1 only transiently binds to DNA and carries the CCAAT-displacement activity, CDP/Cux p110 makes a stable interaction with DNA and stimulates expression of genes such as POLA1.
Protein Name Homeobox Protein Cut-Like 1
Ccaat Displacement Protein
Cdp
Cdp/Cux P200
Homeobox Protein Cux-1 Cleaved Into - Cdp/Cux P110
Database Links Reactome: R-HSA-6811438
Reactome: R-HSA-1839117
Reactome: R-HSA-5655302
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Cut-Like 1 antibody
Anti-Ccaat Displacement Protein antibody
Anti-Cdp antibody
Anti-Cdp/Cux P200 antibody
Anti-Homeobox Protein Cux-1 Cleaved Into - Cdp/Cux P110 antibody
Anti-CUX1 antibody
Anti-CUTL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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