产品详情
简单介绍:
Anti-CD20/MS4A1 antibody (C-Term) (STJ70052)
详情介绍:
Host: | Goat |
Applications: | Pep-ELISA/WB/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-CD20/MS4A1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.01-0.05µg/ml IF-Strong expression of the protein seen in the membranes of Jurkat and in the nuclei and cytoplasm of U2OS cells. 10µg/ml ELISA-antibody detection limit dilution 1:128000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | MS4A1 |
Gene ID: | 931 |
Uniprot ID: | CD20_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_068769.2; NP_690605.1 |
Specificity: | Please note that both reported variants (NP_068769.2 and NP_690605.1) encode the same protein. |
Immunogen Sequence: | CQDQESSPIENDSSP |
Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
Protein Name | B-Lymphocyte Antigen Cd20 B-Lymphocyte Surface Antigen B1 Bp35 Leukocyte Surface Antigen Leu-16 Membrane-Spanning 4-Domains Subfamily A Member 1 Cd Antigen Cd20 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Lipid-Anchor Constitutively Associated With Membrane Rafts |
Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibody Anti-B-Lymphocyte Surface Antigen B1 antibody Anti-Bp35 antibody Anti-Leukocyte Surface Antigen Leu-16 antibody Anti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibody Anti-Cd Antigen Cd20 antibody Anti-MS4A1 antibody Anti-CD20 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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