产品详情
简单介绍:
Mouse ACAT1 (Acetyl Coenzyme A Acetyltransferase 1) Sandwich ELISA Kit (STJE0006835)
详情介绍:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.052ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This ACAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Acat1 |
Gene ID: | 110446 |
Uniprot ID: | THIL_MOUSE |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Succinylation at Lys-265, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5. |
Function | This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. |
Protein Name | Acetyl-Coa Acetyltransferase - Mitochondrial Acetoacetyl-Coa Thiolase |
Database Links | Reactome: R-MMU-70895 Reactome: -MMU-77108 Reactome: -MMU-77111 |
Cellular Localisation | Mitochondrion |
Alternative ELISA Names | Acetyl-Coa Acetyltransferase - Mitochondrial ELISA kit Acetoacetyl-Coa Thiolase ELISA kit Acat1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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