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  • 产品名称：Anti-CYP51A1 antibody (210-290 aa) (STJ190290)

  • 产品型号：STJ190290
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CYP51A1 antibody (210-290 aa) (STJ190290)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Lanosterol 14-alpha demethylase (210-290 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYP51A1
Gene ID: 1595
Uniprot ID: CP51A_HUMAN
Immunogen Region: 210-290 aa
Specificity: CP51A Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 210-290
Function Sterol 14alpha-demethylase that plays a critical role in the cholesterol biosynthesis pathway, being cholesterol the major sterol component in mammalian membranes as well as a precursor for bile acid and steroid hormone synthesis. Cytochrome P450 monooxygenase that catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of sterols such as lanosterol (lanosta-8,24-dien-3beta-ol) and 24,25-dihydrolanosterol (DHL) in the form of formate, and converts the sterols to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol and 4,4-dimethyl-8,14-cholestadien-3beta-ol, respectively, which are intermediates of cholesterol biosynthesis. Can also demethylate substrates not intrinsic to mammals, such as eburicol (24-methylene-24,25-dihydrolanosterol), but at a lower rate than DHL.
Protein Name Lanosterol 14-Alpha Demethylase
Ldm
Cypli
Cytochrome P450 51a1
Cyp51a1
Cytochrome P450-14dm
Cytochrome P45014dm
Cytochrome P450li
Sterol 14-Alpha Demethylase
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-211976
Reactome: R-HSA-2426168
Reactome: R-HSA-9619665
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Microsome Membrane
Alternative Antibody Names Anti-Lanosterol 14-Alpha Demethylase antibody
Anti-Ldm antibody
Anti-Cypli antibody
Anti-Cytochrome P450 51a1 antibody
Anti-Cyp51a1 antibody
Anti-Cytochrome P450-14dm antibody
Anti-Cytochrome P45014dm antibody
Anti-Cytochrome P450li antibody
Anti-Sterol 14-Alpha Demethylase antibody
Anti-CYP51A1 antibody
Anti-CYP51 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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