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  • 产品名称：Mouse DLD (Dihydrolipoyl Dehydrogenase) Sandwich ELISA Kit (STJE0008451)

  • 产品型号：STJE0008451
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse DLD (Dihydrolipoyl Dehydrogenase) Sandwich ELISA Kit (STJE0008451)
详情介绍：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.08ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This DLD Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Dld
Gene ID: 13382
Uniprot ID: DLDH_MOUSE
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Expressed in liver (at protein level).
Post Translational Modifications Tyrosine phosphorylated.
Function Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. In monomeric form may have additional moonlighting function as serine protease. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
Protein Name Dihydrolipoyl Dehydrogenase - Mitochondrial
Dihydrolipoamide Dehydrogenase
Database Links Reactome: R-MMU-204174
Reactome: -MMU-389661
Reactome: -MMU-5362517
Reactome: -MMU-6783984
Reactome: -MMU-70268
Reactome: -MMU-70895
Reactome: -MMU-71064
Reactome: -MMU-71403
Cellular Localisation Mitochondrion Matrix
Nucleus
Cell Projection
Cilium
Flagellum
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome
Mainly Localizes In The Mitochondrion
A Small Fraction Localizes To The Nucleus
Where The 2-Oxoglutarate Dehydrogenase Complex Is Required For Histone Succinylation
Alternative ELISA Names Dihydrolipoyl Dehydrogenase - Mitochondrial ELISA kit
Dihydrolipoamide Dehydrogenase ELISA kit
Dld ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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