产品详情
简单介绍:
Anti-DBI antibody (1-104) (STJ27323)
详情介绍:
Host: | Rabbit |
Applications: | WB/IP |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DBI (1-104) is suitable for use in Western Blot and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IP 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DBI |
Gene ID: | 1622 |
Uniprot ID: | ACBP_HUMAN |
Immunogen Region: | 1-104 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human DBI (NP_001171513.1). |
Immunogen Sequence: | MWGDLWLLPPASANPGTGTE AEFEKAAEEVRHLKTKPSDE EMLFIYGHYKQATVGDINTE RPGMLDFTGKAKWDAWNELK GTSKEDAMKAYINKVEELKK KYGI |
Tissue Specificity | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
Function | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
Protein Name | Acyl-Coa-Binding Protein Acbp Diazepam-Binding Inhibitor Dbi Endozepine Ep |
Database Links | Reactome: R-HSA-77289 |
Cellular Localisation | Endoplasmic Reticulum Golgi Apparatus Golgi Localization Is Dependent On Ligand Binding |
Alternative Antibody Names | Anti-Acyl-Coa-Binding Protein antibody Anti-Acbp antibody Anti-Diazepam-Binding Inhibitor antibody Anti-Dbi antibody Anti-Endozepine antibody Anti-Ep antibody Anti-DBI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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